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Evidence of positive selection in mitochondrial complexes I and V of the African elephant.
(Public Library of Science, 4/2/2014)
As species evolve, they become adapted to their local environments. Detecting the genetic signature of selection and connecting that to the phenotype of the organism, however, is challenging. Here we report using an ...
Sequence-based antigenic change prediction by a sparse learning method incorporating co-evolutionary information.
(Public Library of Science, 9/4/2014)
Rapid identification of influenza antigenic variants will be critical in selecting optimal vaccine candidates and thus a key to developing an effective vaccination program. Recent studies suggest that multiple simultaneous ...