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Spatiotemporal structure of molecular evolution of H5N1 highly pathogenic avian influenza viruses in Vietnam.
(Public Library of Science, 1/8/2010)
BACKGROUND: Vietnam is one of the countries most affected by outbreaks of H5N1 highly pathogenic avian influenza viruses. First identified in Vietnam in poultry in 2001 and in humans in 2004, the virus has since caused 111 ...
A perspective on multiple waves of influenza pandemics.
(Public Library of Science, 4/23/2013)
BACKGROUND: A striking characteristic of the past four influenza pandemic outbreaks in the United States has been the multiple waves of infections. However, the mechanisms responsible for the multiple waves of influenza ...
Sequence-based antigenic change prediction by a sparse learning method incorporating co-evolutionary information.
(Public Library of Science, 9/4/2014)
Rapid identification of influenza antigenic variants will be critical in selecting optimal vaccine candidates and thus a key to developing an effective vaccination program. Recent studies suggest that multiple simultaneous ...