Browsing Honors Theses by Author "Hoffman, Federico"

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Impact of single amino acid mutations in the rhomboid protease Pcp1p on Pcp1p catalytic activity, cellular respiration, mitochondrial morphology, and mitochondrial DNA maintenance

Both, Andries Pieter (Mississippi State UniversityJudy and Bobby Shackouls Honors CollegeDepartment of Biochemistry, Molecular Biology, Entomology and Plant PathologyJudy and Bobby Shackouls Honors CollegeCollege of Agriculture and Life SciencesHonors Office of Undergraduate Research, 2016-05)

Pcp1p is a rhomboid protease in the inner mitochondrial membrane of S. cerevisiae that processes Mgm1p, a protein required for mitochondrial fusion. In this study, five previously generated pcp1 mutant strains were analyzed ...