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dc.contributor.advisorVarela-Stokes, Andreaen_US
dc.contributor.authorHarper, Amanda Bentonen_US
dc.description.abstractTicks can pass a variety of organisms to humans, resulting in mild flu-like illnesses or more severe diseases that may be fatal if not treated. One group of tick-borne organisms of interest to us are rickettsiae, which cause an illness known as spotted fever rickettsiosis. The ticks that transmit rickettsiae to humans may also pass these organisms to animals and to other ticks, which allows for these organisms to continue to circulate in nature. In some cases, two rickettsiae will utilize the same tick host, and occasionally this presents itself as co-infection of the bacteria. Co-infection can then lead to altered distribution of the bacteria in the tick tissues and impact the modes of transmission of one or both bacteria. In this study, our goal was to locate two species of rickettsial bacteria, one that causes disease and one that is not known to, in infected ticks using two different microscopy methods. We found that, while we could tell the two species apart using fluorescence microscopy, and identify whole bacteria in specific tissues using electron microscopy, we had to rely on DNA testing to screen samples, and found inconsistent results. These techniques would likely be inefficient if pursued on a larger scale, which leads us to suggest an alternative technique for future studies.en_US
dc.description.sponsorshipThis research was funded by NIH R15AI099928-01A1.en_US
dc.publisherMississippi State Universityen_US
dc.publisherJudy and Bobby Shackouls Honors Collegeen_US
dc.relation.ispartofseriesJudy and Bobby Shackouls Honors College Undergraduate Senior Thesesen_US
dc.subject.lcshUniversities and colleges--Honors coursesen_US
dc.subject.otherGulf Coast ticken_US
dc.subject.otherAmblyomma maculatumen_US
dc.subject.othermicroscopic analysisen_US
dc.subject.otherspotted fever rickettsiosisen_US
dc.titleMicroscopic analysis of Rickettsial co-infection in the Gulf Coast tick, Amblyomma maculatumen_US
dc.typeHonors Thesisen_US
dc.publisher.departmentDepartment of Biochemistry, Molecular Biology, Entomology and Plant Pathologyen_US
dc.publisher.collegeJudy and Bobby Shackouls Honors Collegeen_US
dc.publisher.collegeCollege of Agriculture and Life Sciencesen_US
dc.publisher.officeHonors Office of Undergraduate Researchen_US
dc.contributor.issuingbodyMississippi State Universityen_US
dc.source.institutionMississippi State Universityen_US
dc.contributor.committeeGoddard, Jeromeen_US
dc.contributor.committeeOppenheimer, Seth F.en_US

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  • Honors Theses
    Theses written by students of the Judy and Bobby Shackouls Honors College.

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