Now showing items 1-15 of 18

    • Stallion sperm transcriptome comprises functionally coherent coding and regulatory RNAs as revealed by microarray analysis and RNA-seq. 

      Das, Pranab J.; McCarthy, Fiona M.; Vishnoi, Monika; Paria, Nandina; Gresham, Cathy; Li, Gang; Kachroo, Priyanka; Sudderth, A. Kendrick; Teague, Sheila; Love, Charles C.; Varner, Dickson D.; Chowdhary, Bhanu P.; Raudsepp, Terje (Public Library of ScienceDepartment of Basic SciencesDepartment of Computer Sciences and EngineeringCollege of Veterinary MedicineJames Worth Bagley College of Engineering, 2/11/2013)
      Mature mammalian sperm contain a complex population of RNAs some of which might regulate spermatogenesis while others probably play a role in fertilization and early development. Due to this limited knowledge, the biological ...
    • Tricarboxylic acid cycle and one-carbon metabolism pathways are important in Edwardsiella ictaluri virulence. 

      Dahal, Neeti; Abdelhamed, Hossam; Lu, Jingjun; Karsi, Attila; Lawrence, Mark L. (Public Library of ScienceDepartment of Basic SciencesCollege of Veterinary Medicine, 6/7/2013)
      Edwardsiella ictaluri is a Gram-negative facultative intracellular pathogen causing enteric septicemia of channel catfish (ESC). The disease causes considerable economic losses in the commercial catfish industry in the ...
    • Evidence of positive selection in mitochondrial complexes I and V of the African elephant. 

      Finch, Tabitha M.; Zhao, Nan; Korkin, Dmitry; Frederick, Katy H.; Eggert, Lori S. (Public Library of ScienceDepartment of Basic SciencesCollege of Veterinary Medicine, 4/2/2014)
      As species evolve, they become adapted to their local environments. Detecting the genetic signature of selection and connecting that to the phenotype of the organism, however, is challenging. Here we report using an ...
    • Identifying blood biomarkers and physiological processes that distinguish humans with superior performance under psychological stress. 

      Cooksey, Amanda M.; Momen, Nausheen; Stocker, Russell; Burgess, Shane C. (Public Library of ScienceDepartment of Basic SciencesDepartment of Mathematics and StatisticsCollege of Veterinary MedicineCollege of Arts and Sciences, 12/18/2009)
      BACKGROUND: Attrition of students from aviation training is a serious financial and operational concern for the U.S. Navy. Each late stage navy aviator training failure costs the taxpayer over $1,000,000 and ultimately ...
    • A joint matrix completion and filtering model for influenza serological data integration. 

      Yuan, Xiao-Tong; Zhang, Tong; Wan, Xiu-Feng (Public Library of ScienceDepartment of Basic SciencesCollege of Veterinary Medicine, 7/25/2013)
      Antigenic characterization based on serological data, such as Hemagglutination Inhibition (HI) assay, is one of the routine procedures for influenza vaccine strain selection. In many cases, it would be impossible to measure ...
    • Sequence-based antigenic change prediction by a sparse learning method incorporating co-evolutionary information. 

      Yang, Jialiang; Zhang, Tong; Wan, Xiu-Feng (Public Library of ScienceDepartment of Basic SciencesCollege of Veterinary Medicine, 9/4/2014)
      Rapid identification of influenza antigenic variants will be critical in selecting optimal vaccine candidates and thus a key to developing an effective vaccination program. Recent studies suggest that multiple simultaneous ...
    • Extreme Evolutionary Conservation of Functionally Important Regions in H1N1 Influenza Proteome 

      Warren, Samantha; Wan, Xiu-Feng; Conant, Gavin; Korkin, Dmitry (Public Library of ScienceDepartment of Basic SciencesCollege of Veterinary Medicine, 11/25/2013)
    • Investigation of the role of TNF-? converting enzyme (TACE) in the inhibition of cell surface and soluble TNF-? production by acute ethanol exposure. 

      von Maltzan, Kristine; Tan, Wei; Pruett, Stephen B. (Public Library of ScienceDepartment of Basic SciencesCollege of Veterinary Medicine, 2/3/2012)
      Toll-like receptors (TLRs) play a fundamental role in the immune system by detecting pathogen associated molecular patterns (PAMPs) to sense host infection. Ethanol at doses relevant for humans inhibits the pathogen induced ...
    • Re-annotation is an essential step in systems biology modeling of functional genomics data. 

      van den Berg, Bart H. J.; McCarthy, Fiona M.; Lamont, Susan J.; Burgess, Shane C. (Public Library of ScienceDepartment of Basic SciencesCollege of Veterinary Medicine, 5/14/2010)
      One motivation of systems biology research is to understand gene functions and interactions from functional genomics data such as that derived from microarrays. Up-to-date structural and functional annotations of genes are ...
    • Salmonella in broiler litter and properties of soil at farm location. 

      Volkova, Victoriya V.; Bailey, R. Hartford; Wills, Robert W. (Public Library of ScienceDepartment of Pathobiology and Population MedicineCollege of Veterinary Medicine, 7/28/2009)
      Contamination of litter in a broiler grow-out house with Salmonella prior to placement of a new flock has been shown to be a precursor of the flock's Salmonella contamination further down the production continuum. In the ...
    • Proteomics-based systems biology modeling of bovine germinal vesicle stage oocyte and cumulus cell interaction. 

      Peddinti, Divyaswetha; Memili, Erdogan; Burgess, Shane C. (Public Library of ScienceDepartment of Basic SciencesDepartment of Animal and Dairy SciencesCollege of Veterinary MedicineCollege of Agriculture and Life SciencesInstitute for Digital Biology, 6/21/2010)
      BACKGROUND: Oocytes are the female gametes which establish the program of life after fertilization. Interactions between oocyte and the surrounding cumulus cells at germinal vesicle (GV) stage are considered essential for ...
    • A perspective on multiple waves of influenza pandemics. 

      Mummert, Anna; Weiss, Howard; Long, Li-Ping; Amigó, José M; Wan, Xiu-Feng (Public Library of ScienceDepartment of Basic SciencesCollege of Veterinary Medicine, 4/23/2013)
      BACKGROUND: A striking characteristic of the past four influenza pandemic outbreaks in the United States has been the multiple waves of infections. However, the mechanisms responsible for the multiple waves of influenza ...
    • Ultrasonic incisions produce less inflammatory mediator response during early healing than electrosurgical incisions. 

      Nanduri, Bindu; Pendarvis, Ken; Shack, Leslie A.; Kumar, Ranjit; Clymer, Jeffrey W.; Korvick, Donna L.; Burgess, Shane C. (Public Library of ScienceDepartment of Basic SciencesCollege of Veterinary Medicine, 9/12/2013)
      As the use of laparoscopic surgery has become more widespread in recent years, the need has increased for minimally-invasive surgical devices that effectively cut and coagulate tissue with reduced tissue trauma. Although ...
    • Cross-Ontology multi-level association rule mining in the Gene Ontology. 

      Manda, Prashanti; Ozkan, Seval; Wang, Hui; McCarthy, Fiona M.; Bridges, Susan M. (Public Library of ScienceDepartment of Computer Sciences and EngineeringDepartment of Plant and Soil SciencesDepartment of Basic SciencesJames Worth Bagley College of EngineeringCollege of Agriculture and Life SciencesCollege of Veterinary MedicineInstitute for Genomics, Biocomputing and Biotechnology, 10/12/2012)
      The Gene Ontology (GO) has become the internationally accepted standard for representing function, process, and location aspects of gene products. The wealth of GO annotation data provides a valuable source of implicit ...
    • Spatiotemporal structure of molecular evolution of H5N1 highly pathogenic avian influenza viruses in Vietnam. 

      Carrel, Margaret A.; Emch, Michael; Jobe, R. Todd; Moody, Aaron; Wan, Xiu-Feng (Public Library of ScienceDepartment of Basic SciencesCollege of Veterinary Medicine, 1/8/2010)
      BACKGROUND: Vietnam is one of the countries most affected by outbreaks of H5N1 highly pathogenic avian influenza viruses. First identified in Vietnam in poultry in 2001 and in humans in 2004, the virus has since caused 111 ...